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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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6
7
8
9
10
11
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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260 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
ACKR4
ENSSSCG00000011630
ENSG00000129048
Atypical chemokine receptor 4
Tissue enhanced
Detected in many
adipose tissue:
28.7
ovary:
33.6
ADA
ENSSSCG00000021255
ENSG00000196839
Adenosine deaminase
Tissue enhanced
Detected in many
mouth:
124.3
small intestine:
43.7
stomach:
31.6
ADAM17
ENSSSCG00000008641
ENSG00000151694
Disintegrin and metalloproteinase domain-containing protein 17 precursor
Low tissue specificity
Detected in all
ADAMTS10
ENSSSCG00000026994
ENSG00000142303
A disintegrin and metalloproteinase with thrombospondin motifs 10 precursor
Low tissue specificity
Detected in many
ADGRE5
ENSSSCG00000013775
ENSG00000123146
Adhesion G protein-coupled receptor E5
Low tissue specificity
Detected in many
ADRA2A
ENSSSCG00000010629
ENSG00000150594
Alpha-2A adrenergic receptor
Tissue enhanced
Detected in many
gallbladder:
51.0
stomach:
34.8
AHR
ENSSSCG00000030484
ENSG00000106546,ENSG00000283321
Aryl hydrocarbon receptor
Low tissue specificity
Detected in all
ANKRD13A
ENSSSCG00000009924
ENSG00000076513
Ankyrin repeat domain 13A
Low tissue specificity
Detected in all
ARAP1
ENSSSCG00000014817
ENSG00000186635
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Low tissue specificity
Detected in all
ARF6
ENSSSCG00000005012
ENSG00000165527
ADP-ribosylation factor 6
Low tissue specificity
Detected in all
ARHGAP17
ENSSSCG00000031488
ENSG00000140750
Rho GTPase activating protein 17
Low tissue specificity
Detected in all
ARHGEF1
ENSSSCG00000003040
ENSG00000076928
Rho guanine nucleotide exchange factor 1
Tissue enhanced
Detected in many
cartilage:
50.5
lymphoid tissue:
50.4
ARID5B
ENSSSCG00000010219
ENSG00000150347
AT-rich interaction domain 5B
Low tissue specificity
Detected in all
B3GNT3
ENSSSCG00000013886
ENSG00000179913
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Tissue enhanced
Detected in many
male glands:
34.7
stomach:
49.8
BACH1
ENSSSCG00000012029
ENSG00000156273
BTB domain and CNC homolog 1
Low tissue specificity
Detected in all
BCL10
ENSSSCG00000025691
ENSG00000142867
B-cell lymphoma/leukemia 10
Low tissue specificity
Detected in all
BCL3
ENSSSCG00000027426
ENSG00000069399
B-cell lymphoma 3 protein
Tissue enhanced
Detected in many
mesothelial tissue:
52.6
BCL6
ENSSSCG00000011810
ENSG00000113916
B-cell lymphoma 6 protein
Low tissue specificity
Detected in all
C15orf39
ENSSSCG00000001885
ENSG00000167173
Chromosome 15 open reading frame 39
Low tissue specificity
Detected in many
CAPN1
ENSSSCG00000012999
ENSG00000014216
Calpain-1 catalytic subunit
Low tissue specificity
Detected in all
CARD9
ENSSSCG00000031715
ENSG00000187796
Caspase recruitment domain family member 9
Tissue enhanced
Detected in many
lymphoid tissue:
36.5
CASP7
ENSSSCG00000032408
ENSG00000165806
Caspase 7
Low tissue specificity
Detected in many
CBFA2T3
ENSSSCG00000002648
ENSG00000129993
CBFA2/RUNX1 translocation partner 3
Low tissue specificity
Detected in many
CBLB
ENSSSCG00000022486
ENSG00000114423
Cbl proto-oncogene B
Low tissue specificity
Detected in all
CCDC71L
ENSSSCG00000015436
ENSG00000253276
Coiled-coil domain containing 71 like
Tissue enhanced
Detected in many
adrenal gland:
42.2
CCL21
ENSSSCG00000038162
ENSG00000137077
C-C motif chemokine 21 precursor
Tissue enhanced
Detected in all
lymphoid tissue:
111.9
ovary:
39.7
CD44
ENSSSCG00000013297
ENSG00000026508
CD44 molecule (Indian blood group)
Tissue enhanced
Detected in many
male glands:
96.2
salivary gland:
142.4
CD58
ENSSSCG00000006738
ENSG00000116815
Lymphocyte function-associated antigen 3 precursor
Low tissue specificity
Detected in all
CDC25B
ENSSSCG00000007151
ENSG00000101224
M-phase inducer phosphatase 2
Tissue enhanced
Detected in many
lymphoid tissue:
46.1
stomach:
54.1
CEBPA
ENSSSCG00000002866
ENSG00000245848
CCAAT/enhancer binding protein alpha
Tissue enhanced
Detected in many
adipose tissue:
149.5
bone marrow:
77.5
CEP85L
ENSSSCG00000004249
ENSG00000111860
Centrosomal protein 85 like
Low tissue specificity
Detected in all
CFD
ENSSSCG00000013418
ENSG00000197766
Complement factor D
Tissue enhanced
Detected in many
gallbladder:
125.8
small intestine:
98.3
stomach:
122.6
CISH
ENSSSCG00000040581
ENSG00000114737
Cytokine-inducible SH2-containing protein
Tissue enhanced
Detected in many
liver:
30.9
CMTM3
ENSSSCG00000038151
ENSG00000140931
CKLF like MARVEL transmembrane domain containing 3
Low tissue specificity
Detected in many
COLGALT1
ENSSSCG00000013883
ENSG00000130309
Collagen beta(1-O)galactosyltransferase 1
Low tissue specificity
Detected in all
CORO1B
ENSSSCG00000012920
ENSG00000172725
Coronin 1B
Low tissue specificity
Detected in all
CSF1
ENSSSCG00000037449
ENSG00000184371
Macrophage colony-stimulating factor 1 precursor
Tissue enhanced
Detected in many
synovial tissue:
59.3
CSF3
ENSSSCG00000017488
ENSG00000108342
Granulocyte colony-stimulating factor
Tissue enhanced
Detected in many
aorta:
12.8
mesothelial tissue:
26.2
CTRC
ENSSSCG00000027215
ENSG00000162438
Chymotrypsin-C precursor
Tissue enhanced
Detected in some
adipose tissue:
4.4
gallbladder:
9.4
mesothelial tissue:
4.2
CTSC
ENSSSCG00000014924
ENSG00000109861
Cathepsin C
Tissue enriched
Detected in many
ovary:
200.8
CXCL12
ENSSSCG00000034973
ENSG00000107562
Stromal cell-derived factor 1 precursor
Tissue enhanced
Detected in many
bone marrow:
71.3
lymphoid tissue:
82.7
CYP2S1
ENSSSCG00000032803
ENSG00000167600
Cytochrome P450 family 2 subfamily S member 1
Tissue enhanced
Detected in many
stomach:
41.0
DIAPH2
ENSSSCG00000012474
ENSG00000147202
Diaphanous related formin 2
Low tissue specificity
Detected in all
DNAJC14
ENSSSCG00000000366
ENSG00000135392
DnaJ homolog subfamily C member 14
Low tissue specificity
Detected in all
DRAM1
ENSSSCG00000023972
ENSG00000136048
DNA damage-regulated autophagy modulator protein 1
Tissue enhanced
Detected in many
ovary:
30.5
DUSP4
ENSSSCG00000015850
ENSG00000120875
Dual specificity phosphatase 4
Tissue enhanced
Detected in many
ovary:
53.6
EFHD2
ENSSSCG00000003458
ENSG00000142634
EF-hand domain family member D2
Tissue enhanced
Detected in all
stomach:
162.8
EHBP1L1
ENSSSCG00000012988
ENSG00000173442
EH domain binding protein 1 like 1
Low tissue specificity
Detected in many
ELF1
ENSSSCG00000009440
ENSG00000120690
E74 like ETS transcription factor 1
Low tissue specificity
Detected in all
ELF4
ENSSSCG00000012656
ENSG00000102034
E74 like ETS transcription factor 4
Tissue enhanced
Detected in many
stomach:
41.7
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